Version 5.4
Mus musculus Gene: Scyl2
Summary
InnateDB Gene IDBG-184428.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scyl2
Gene Name SCY1-like 2 (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000069539
Encoded Proteins
IDBP-184430
SCY1-like 2 (S. cerevisiae)
IDBP-625370
SCY1-like 2 (S. cerevisiae)
IDBP-625375
SCY1-like 2 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136021:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:89638721-89686285
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000092227 ENSMUSP00000089874
ENSMUST00000105294
ENSMUST00000174252 ENSMUSP00000133992
ENSMUST00000173526
ENSMUST00000174492 ENSMUSP00000134366
ENSMUST00000174575
ENSMUST00000174429
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005102 receptor binding
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0002092 positive regulation of receptor internalization
GO:0006468 protein phosphorylation
GO:0008333 endosome to lysosome transport
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway
GO:2000370 positive regulation of clathrin-mediated endocytosis
Cellular Component
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0030136 clathrin-coated vesicle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136021
View Gene Order
ENSBTAG00000013859
Not yet available
Cross-References
SwissProt Q8CFE4
TrEMBL
UniProt Splice Variant
Entrez Gene 213326
UniGene Mm.27651
RefSeq NM_198021 XM_006513458 XM_006513459
OMIM
CCDS CCDS36027
HPRD
IMGT
MGI ID MGI:1289172
MGI Symbol Scyl2
EMBL AK136092 AK139747 BC030932 BC042443
GenPept AAH30932 AAH42443 BAE22815 BAE24123
RNA Seq Atlas 213326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca