Version 5.4
Homo sapiens Gene: SCYL2
Summary
InnateDB Gene IDBG-52827.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCYL2
Gene Name SCY1-like 2 (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136021
Encoded Proteins
IDBP-52829
SCY1-like 2 (S. cerevisiae)
IDBP-601980
SCY1-like 2 (S. cerevisiae)
IDBP-600862
SCY1-like 2 (S. cerevisiae)
IDBP-594951
SCY1-like 2 (S. cerevisiae)
IDBP-585321
SCY1-like 2 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:100267140-100341724
Strand Forward strand
Band q23.1
Transcripts
ENST00000360820 ENSP00000354061
ENST00000549687 ENSP00000448366
ENST00000548392 ENSP00000450294
ENST00000550067
ENST00000549486
ENST00000550251 ENSP00000449567
ENST00000553148
ENST00000548871 ENSP00000448400
ENST00000547202
ENST00000547735
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005102 receptor binding
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0002092 positive regulation of receptor internalization
GO:0006468 protein phosphorylation
GO:0008333 endosome to lysosome transport
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway
GO:2000370 positive regulation of clathrin-mediated endocytosis
Cellular Component
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0030136 clathrin-coated vesicle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000069539
View Gene Order
ENSBTAG00000013859
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 55681
UniGene Hs.506481 Hs.611717
RefSeq NM_017988 XM_005269018
HUGO HGNC:19286
OMIM
CCDS CCDS9076
HPRD 07642
IMGT
EMBL
GenPept
RNA Seq Atlas 55681

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca