Version 5.4
Mus musculus Gene: Krt81
Summary
InnateDB Gene IDBG-185940.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt81
Gene Name keratin 81
Synonyms AA589625; Krt2-19
Species Mus musculus
Ensembl Gene ENSMUSG00000067615
Encoded Proteins
IDBP-185942
keratin 81
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205426:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:101459061-101463765
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000061185 ENSMUSP00000056525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005882 intermediate filament
GO:0045095 keratin filament
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000205426
View Gene Order
Cross-References
SwissProt Q9ERE2
TrEMBL
UniProt Splice Variant
Entrez Gene 64818
UniGene
RefSeq NM_001166157
OMIM
CCDS CCDS49734
HPRD
IMGT
MGI ID MGI:1928858
MGI Symbol Krt81
EMBL AC103674 AC157583 AF312018
GenPept AAG34120
RNA Seq Atlas 64818

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca