Mus musculus Gene: Krt81
Summary
InnateDB Gene IDBG-185940.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt81
Gene Name keratin 81
Synonyms AA589625; Krt2-19;
Species Mus musculus
Ensembl Gene ENSMUSG00000067615
Encoded Proteins
keratin 81
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205426:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:101459061-101463765
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000061185 ENSMUSP00000056525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005882 intermediate filament
GO:0045095 keratin filament
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt Q9ERE2
TrEMBL
UniProt Splice Variant
Entrez Gene 64818
UniGene
RefSeq NM_001166157
OMIM
CCDS CCDS49734
HPRD
IMGT
MGI ID MGI:1928858
MGI Symbol Krt81
EMBL AC103674 AC157583 AF312018
GenPept AAG34120
RNA Seq Atlas 64818