Version 5.4
| Homo sapiens Gene: KRT81 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-34254.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | KRT81 | ||||||||||||||||||
| Gene Name | keratin 81 | ||||||||||||||||||
| Synonyms | ghHkb1; Hb-1; HB1; hHAKB2-1; KRTHB1; MLN137 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000205426 | ||||||||||||||||||
| Encoded Proteins |
keratin 81
keratin 81
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 12:52285913-52291534 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q13.13 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||||||||||||
| SwissProt | Q14533 | ||||||||||||||||||
| TrEMBL | Q8N120 Q8NFV1 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 3887 | ||||||||||||||||||
| UniGene | Hs.658118 Hs.683440 | ||||||||||||||||||
| RefSeq | NM_002281 | ||||||||||||||||||
| HUGO | HGNC:6458 | ||||||||||||||||||
| OMIM | 602153 | ||||||||||||||||||
| CCDS | CCDS31805 | ||||||||||||||||||
| HPRD | 03691 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC121757 AF416705 AY121753 AY123848 AY152544 BC006452 BC021241 BC117465 BC117467 S75796 X80197 X81420 Y13621 | ||||||||||||||||||
| GenPept | AAB32813 AAH06452 AAH21241 AAI17466 AAI17468 AAM92877 AAM94951 AAN04663 AAN75226 CAA56488 CAA57180 CAA73943 | ||||||||||||||||||
| RNA Seq Atlas | 3887 | ||||||||||||||||||