Version 5.4
Mus musculus Gene: Fbxo9
Summary
InnateDB Gene IDBG-186192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo9
Gene Name f-box protein 9
Synonyms 9030401P18Rik; AA986398
Species Mus musculus
Ensembl Gene ENSMUSG00000001366
Encoded Proteins
IDBP-186194
f-box protein 9
IDBP-186196
f-box protein 9
IDBP-533899
f-box protein 9
IDBP-531531
f-box protein 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112146:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:78081499-78109065
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000085311 ENSMUSP00000082419
ENSMUST00000001402 ENSMUSP00000001402
ENSMUST00000159453
ENSMUST00000162451
ENSMUST00000162310
ENSMUST00000159099 ENSMUSP00000125381
ENSMUST00000162625 ENSMUSP00000123807
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032006 regulation of TOR signaling
GO:0045087 innate immune response
GO:0045444 fat cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112146
View Gene Order
ENSBTAG00000015083
Not yet available
Cross-References
SwissProt Q8BK06
TrEMBL
UniProt Splice Variant
Entrez Gene 71538
UniGene Mm.28584
RefSeq NM_023605 NM_001081490
OMIM
CCDS CCDS52863 CCDS52864
HPRD
IMGT
MGI ID MGI:1918788
MGI Symbol Fbxo9
EMBL AB041585 AK018482 AK077607 BC020074
GenPept AAH20074 BAA95068 BAB31231 BAC36897
RNA Seq Atlas 71538

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca