Version 5.4
Mus musculus Gene: Mto1
Summary
InnateDB Gene IDBG-186878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mto1
Gene Name mitochondrial translation optimization 1 homolog (S. cerevisiae)
Synonyms 2310039H01Rik; 5730419A02Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000032342
Encoded Proteins
IDBP-186880
mitochondrial translation optimization 1 homolog (S. cerevisiae)
IDBP-537263
mitochondrial translation optimization 1 homolog (S. cerevisiae)
IDBP-540264
mitochondrial translation optimization 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135297:
This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:78448208-78475348
Strand Forward strand
Band E1
Transcripts
ENSMUST00000034896 ENSMUSP00000034896
ENSMUST00000148238 ENSMUSP00000121424
ENSMUST00000150850
ENSMUST00000157051
ENSMUST00000133002 ENSMUSP00000123414
ENSMUST00000136478
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0044822 poly(A) RNA binding
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0008033 tRNA processing
GO:0055114 oxidation-reduction process
GO:0070899 mitochondrial tRNA wobble uridine modification
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135297
View Gene Order
ENSBTAG00000016839
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.291779 Mm.388209 Mm.400545
RefSeq NM_026658
OMIM
CCDS CCDS23363
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca