Mus musculus Gene: Ralb
Summary
InnateDB Gene IDBG-187413.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ralb
Gene Name v-ral simian leukemia viral oncogene homolog B (ras related)
Synonyms 5730472O18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000004451
Encoded Proteins
v-ral simian leukemia viral oncogene homolog B (ras related)
v-ral simian leukemia viral oncogene homolog B (ras related)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144118:
This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:119470305-119504794
Strand Reverse strand
Band E2.3
Transcripts
ENSMUST00000004565 ENSMUSP00000004565
ENSMUST00000142945 ENSMUSP00000119849
ENSMUST00000156213
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0000910 cytokinesis
GO:0001928 regulation of exocyst assembly
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0015031 protein transport
GO:0060178 regulation of exocyst localization
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030496 midbody
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Signalling to RAS pathway
p38MAPK events pathway
Signalling to ERKs pathway
Signalling by NGF pathway
NGF signalling via TRKA from the plasma membrane pathway
Signal Transduction pathway
KEGG
Pancreatic cancer pathway
Pathways in cancer pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
p38MAPK events pathway
Signalling to RAS pathway
Signalling by NGF pathway
Signal Transduction pathway
Signalling to ERKs pathway
NGF signalling via TRKA from the plasma membrane pathway
KEGG
Pancreatic cancer pathway
Pathways in cancer pathway
INOH
PID NCI
CXCR4-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27832 Mm.490754
RefSeq NM_022327 XM_006529782
OMIM
CCDS CCDS15225
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas