Version 5.4
Mus musculus Gene: Plekhg6
Summary
InnateDB Gene IDBG-189899.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekhg6
Gene Name pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038167
Encoded Proteins
IDBP-189901
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000008323:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:125362660-125380793
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000042647 ENSMUSP00000037004
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0000922 spindle pole
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0032154 cleavage furrow
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000008323
View Gene Order
ENSBTAG00000004208
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
rhoa_reg_pathway
Regulation of RhoA activity
Cross-References
SwissProt Q8R0J1
TrEMBL
UniProt Splice Variant
Entrez Gene 213522
UniGene Mm.333396
RefSeq NM_198604 XM_006505867
OMIM
CCDS CCDS39642
HPRD
IMGT
MGI ID MGI:2682298
MGI Symbol Plekhg6
EMBL AC140324 BC026778
GenPept AAH26778
RNA Seq Atlas 213522

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca