Version 5.4
Mus musculus Gene: Nob1
Summary
InnateDB Gene IDBG-190835.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nob1
Gene Name NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
Synonyms 1700021I09Rik; ART-4; Nob1p; Psmd8bp1
Species Mus musculus
Ensembl Gene ENSMUSG00000003848
Encoded Proteins
IDBP-190837
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
IDBP-622279
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
IDBP-622289
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141101:
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:107412486-107425051
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000076585
ENSMUST00000003946 ENSMUSP00000003946
ENSMUST00000109273
ENSMUST00000170796
ENSMUST00000169311 ENSMUSP00000126868
ENSMUST00000163757
ENSMUST00000163973
ENSMUST00000165266 ENSMUSP00000129298
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0046872 metal ion binding
Biological Process
GO:0007601 visual perception
GO:0030490 maturation of SSU-rRNA
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141101
View Gene Order
ENSBTAG00000020633
Not yet available
Cross-References
SwissProt Q8BW10
TrEMBL E9PW56 Q148S3
UniProt Splice Variant
Entrez Gene 67619
UniGene Mm.334793 Mm.403649
RefSeq NM_026277
OMIM
CCDS CCDS22649
HPRD
IMGT
MGI ID MGI:1914869
MGI Symbol Nob1
EMBL AC158364 AK021194 AK075755 BC054835 BC103793 BC117992 BC117993 CH466525
GenPept AAH54835 AAI03794 AAI17993 AAI17994 BAB32325 BAC35933 EDL11408
RNA Seq Atlas 67619

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca