InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Dhx38

Summary

InnateDB Gene

IDBG-191132.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dhx38

Gene Name

DEAH (Asp-Glu-Ala-His) box polypeptide 38

Synonyms

5730550P09Rik; AI325984; AW540902; Ddx38; mKIAA0224; Prp16

Species

Mus musculus

Ensembl Gene

ENSMUSG00000037993

Encoded Proteins

IDBP-191134

DEAH (Asp-Glu-Ala-His) box polypeptide 38

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140829:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:109548017-109565601

Strand

Reverse strand

Band

Transcripts

ENSMUST00000042601

ENSMUSP00000047865

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0044822	poly(A) RNA binding