Version 5.4
| Mus musculus Gene: Mpdu1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-191386.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Mpdu1 | ||||||||
| Gene Name | mannose-P-dolichol utilization defect 1 | ||||||||
| Synonyms | LEC35; SL15; Supl15h | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000018761 | ||||||||
| Encoded Proteins |
mannose-P-dolichol utilization defect 1
mannose-P-dolichol utilization defect 1
mannose-P-dolichol utilization defect 1
mannose-P-dolichol utilization defect 1
mannose-P-dolichol utilization defect 1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene encodes a member of the PQ-loop superfamily. A similar gene in human encodes a protein that is required for monosaccharide-P-dolichol-dependent glycosyltransferase reactions, and disruption of this gene is the cause of congenital disorder of glycosylation (CDG) type 1F, a disease linked to defects in protein N-glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 11:69656697-69662642 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | B3 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.89579 | ||||||||
| RefSeq | NM_011900 XM_006533310 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS24903 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||