Version 5.4
Mus musculus Gene: Uhrf1
Summary
InnateDB Gene IDBG-191986.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uhrf1
Gene Name ubiquitin-like, containing PHD and RING finger domains, 1
Synonyms AL022808; ICBP90; Np95; RNF106
Species Mus musculus
Ensembl Gene ENSMUSG00000001228
Encoded Proteins
IDBP-191988
ubiquitin-like, containing PHD and RING finger domains, 1
IDBP-254698
ubiquitin-like, containing PHD and RING finger domains, 1
IDBP-254700
ubiquitin-like, containing PHD and RING finger domains, 1
IDBP-254702
ubiquitin-like, containing PHD and RING finger domains, 1
IDBP-626208
ubiquitin-like, containing PHD and RING finger domains, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56303321-56323486
Strand Forward strand
Band D
Transcripts
ENSMUST00000001258 ENSMUSP00000001258
ENSMUST00000113039 ENSMUSP00000108662
ENSMUST00000113038 ENSMUSP00000108661
ENSMUST00000113035 ENSMUSP00000108658
ENSMUST00000142387 ENSMUSP00000125830
ENSMUST00000137876
ENSMUST00000139654
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 28 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008327 methyl-CpG binding
GO:0016874 ligase activity
GO:0031493 nucleosomal histone binding
GO:0035064 methylated histone binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0044729 hemi-methylated DNA-binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006281 DNA repair
GO:0006351 transcription, DNA-templated
GO:0007049 cell cycle
GO:0008283 cell proliferation
GO:0010216 maintenance of DNA methylation
GO:0010390 histone monoubiquitination
GO:0016574 histone ubiquitination
GO:0032270 positive regulation of cellular protein metabolic process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0051865 protein autoubiquitination
Cellular Component
GO:0000790 nuclear chromatin
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0005657 replication fork
GO:0005720 nuclear heterochromatin
GO:0016363 nuclear matrix
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_233572
Gene Expression pathway
REACT_268475
DNA methylation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.42196
RefSeq NM_001111078 NM_001111079 NM_001111080 NM_010931 XM_006523799 XM_006523800
OMIM
CCDS CCDS28903 CCDS50151
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca