Mus musculus Gene: Klrd1
Summary
InnateDB Gene IDBG-192118.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klrd1
Gene Name killer cell lectin-like receptor, subfamily D, member 1
Synonyms CD94;
Species Mus musculus
Ensembl Gene ENSMUSG00000030165
Encoded Proteins
killer cell lectin-like receptor, subfamily D, member 1
killer cell lectin-like receptor, subfamily D, member 1
killer cell lectin-like receptor, subfamily D, member 1
killer cell lectin-like receptor, subfamily D, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134539:
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:129591782-129598775
Strand Forward strand
Band F3
Transcripts
ENSMUST00000032268 ENSMUSP00000032268
ENSMUST00000112063 ENSMUSP00000107694
ENSMUST00000119520 ENSMUSP00000113399
ENSMUST00000159804 ENSMUSP00000123703
ENSMUST00000159077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Innate Immune System pathway
Immune System pathway
DAP12 interactions pathway
DAP12 signaling pathway
KEGG
Antigen processing and presentation pathway
Natural killer cell mediated cytotoxicity pathway
Graft-versus-host disease pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
DAP12 signaling pathway
Innate Immune System pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Adaptive Immune System pathway
Immune System pathway
DAP12 interactions pathway
KEGG
Antigen processing and presentation pathway
Natural killer cell mediated cytotoxicity pathway
Graft-versus-host disease pathway
INOH
PID BIOCARTA
Ras-independent pathway in nk cell-mediated cytotoxicity [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.391515
RefSeq NM_010654 XM_006505655
OMIM
CCDS CCDS57456
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas