Version 5.4
Mus musculus Gene: Aen
Summary
InnateDB Gene IDBG-193491.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aen
Gene Name apoptosis enhancing nuclease
Synonyms 2700083B06Rik; Isg20l1
Species Mus musculus
Ensembl Gene ENSMUSG00000030609
Encoded Proteins
IDBP-266707
apoptosis enhancing nuclease
IDBP-266709
apoptosis enhancing nuclease
IDBP-266711
apoptosis enhancing nuclease
IDBP-539929
apoptosis enhancing nuclease
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181026:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:78895854-78911209
Strand Forward strand
Band D2
Transcripts
ENSMUST00000107425 ENSMUSP00000103048
ENSMUST00000107423 ENSMUSP00000103046
ENSMUST00000107421 ENSMUSP00000103044
ENSMUST00000123824
ENSMUST00000138167 ENSMUSP00000117331
ENSMUST00000172017
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
Biological Process
GO:0010212 response to ionizing radiation
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000181026
View Gene Order
ENSBTAG00000017632
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
p73pathway
p73 transcription factor network
tap63pathway
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.34109 Mm.408229 Mm.420248 Mm.482669
RefSeq NM_001162939 NM_026531 XM_006541137
OMIM
CCDS CCDS39988 CCDS52277
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca