Version 5.4
Mus musculus Gene: Nudt12
Summary
InnateDB Gene IDBG-194470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nudt12
Gene Name nudix (nucleoside diphosphate linked moiety X)-type motif 12
Synonyms 0610016O18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024228
Encoded Proteins
IDBP-194472
nudix (nucleoside diphosphate linked moiety X)-type motif 12
IDBP-626987
nudix (nucleoside diphosphate linked moiety X)-type motif 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112874:
Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and effectors. Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide ratios in response to changing circumstances (Abdelraheim et al., 2003 [PubMed 12790796]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:58999618-59013372
Strand Reverse strand
Band D
Transcripts
ENSMUST00000025065 ENSMUSP00000025065
ENSMUST00000174108
ENSMUST00000174122 ENSMUSP00000133678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000210 NAD+ diphosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0035529 NADH pyrophosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006742 NADP catabolic process
GO:0019677 NAD catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005777 peroxisome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112874
View Gene Order
ENSBTAG00000027728
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00760
Nicotinate and nicotinamide metabolism pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00760
Nicotinate and nicotinamide metabolism pathway
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt Q9DCN1
TrEMBL
UniProt Splice Variant
Entrez Gene 67993
UniGene Mm.36507 Mm.405232 Mm.488508
RefSeq NM_026497 XM_006524834
OMIM
CCDS CCDS28933
HPRD
IMGT
MGI ID MGI:1915243
MGI Symbol Nudt12
EMBL AK002641 BC057657
GenPept AAH57657 BAB22253
RNA Seq Atlas 67993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca