Version 5.4
Mus musculus Gene: Atf7ip
Summary
InnateDB Gene IDBG-194774.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atf7ip
Gene Name activating transcription factor 7 interacting protein
Synonyms 2610204M12Rik; AM; Mcaf1
Species Mus musculus
Ensembl Gene ENSMUSG00000030213
Encoded Proteins
IDBP-194776
activating transcription factor 7 interacting protein
IDBP-787764
activating transcription factor 7 interacting protein
IDBP-787765
activating transcription factor 7 interacting protein
IDBP-787767
activating transcription factor 7 interacting protein
IDBP-787769
activating transcription factor 7 interacting protein
IDBP-787770
activating transcription factor 7 interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171681:
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:136518802-136611038
Strand Forward strand
Band G1
Transcripts
ENSMUST00000032335 ENSMUSP00000032335
ENSMUST00000185724 ENSMUSP00000140458
ENSMUST00000186577 ENSMUSP00000140121
ENSMUST00000185936
ENSMUST00000187429 ENSMUSP00000140502
ENSMUST00000186742 ENSMUSP00000139908
ENSMUST00000189535 ENSMUSP00000139446
ENSMUST00000188805
ENSMUST00000185332
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0016887 ATPase activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006200 ATP catabolic process
GO:0006306 DNA methylation
GO:0006351 transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171681
View Gene Order
ENSBTAG00000003221
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_019426 XM_006506388 XM_006506389 XM_006506390 XM_006506391 XM_006506392
OMIM
CCDS CCDS20651
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca