Mus musculus Gene: Mgp
Summary
InnateDB Gene IDBG-195091.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mgp
Gene Name matrix Gla protein
Synonyms Mglap;
Species Mus musculus
Ensembl Gene ENSMUSG00000030218
Encoded Proteins
matrix Gla protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111341:
The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:136872436-136875805
Strand Reverse strand
Band G1
Transcripts
ENSMUST00000032342 ENSMUSP00000032342
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0001503 ossification
GO:0030154 cell differentiation
GO:0030500 regulation of bone mineralization
GO:0051216 cartilage development
Cellular Component
GO:0005576 extracellular region
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Cross-References
SwissProt P19788
TrEMBL
UniProt Splice Variant
Entrez Gene 17313
UniGene
RefSeq NM_008597
OMIM
CCDS CCDS20659
HPRD
IMGT
MGI ID MGI:96976
MGI Symbol Mgp
EMBL AK018719 BC036991 D00613 S77350
GenPept AAH36991 AAP31997 BAA00488 BAB31365
RNA Seq Atlas 17313