InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Sfn

Summary

InnateDB Gene

IDBG-195282.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sfn

Gene Name

stratifin

Synonyms

Er; Mme1; Ywhas

Species

Mus musculus

Ensembl Gene

ENSMUSG00000047281

Encoded Proteins

IDBP-195284

stratifin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175793:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:133600556-133602168

Strand

Reverse strand

Band

D2.3

Transcripts

ENSMUST00000057311

ENSMUSP00000050374

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 165 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	15 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	165 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0019904	protein domain specific binding
GO:0051219	phosphoprotein binding

Biological Process

GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001836	release of cytochrome c from mitochondria
GO:0003334	keratinocyte development
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010482	regulation of epidermal cell division
GO:0010839	negative regulation of keratinocyte proliferation
GO:0030216	keratinocyte differentiation
GO:0030307	positive regulation of cell growth
GO:0031424	keratinization
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588	skin development
GO:0045606	positive regulation of epidermal cell differentiation
GO:0046827	positive regulation of protein export from nucleus
GO:0051726	regulation of cell cycle
GO:0061436	establishment of skin barrier

Cellular Component

GO:0005576	extracellular region
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030659	cytoplasmic vesicle membrane
GO:0070062	extracellular vesicular exosome