Version 5.4
Mus musculus Gene: Sds
Summary
InnateDB Gene IDBG-195642.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sds
Gene Name serine dehydratase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029597
Encoded Proteins
IDBP-195644
serine dehydratase
IDBP-257158
serine dehydratase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135094:
This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:120476531-120483932
Strand Forward strand
Band F
Transcripts
ENSMUST00000066540 ENSMUSP00000064849
ENSMUST00000111898 ENSMUSP00000107529
ENSMUST00000124978
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003941 L-serine ammonia-lyase activity
GO:0004794 L-threonine ammonia-lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006094 gluconeogenesis
GO:0006565 L-serine catabolic process
GO:0033590 response to cobalamin
GO:0042866 pyruvate biosynthetic process
GO:0043200 response to amino acid
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135094
View Gene Order
ENSBTAG00000031814
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00290
Valine, leucine and isoleucine biosynthesis pathway
mmu00260
Glycine, serine and threonine metabolism pathway
mmu00270
Cysteine and methionine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00290
Valine, leucine and isoleucine biosynthesis pathway
hsa00260
Glycine, serine and threonine metabolism pathway
hsa00270
Cysteine and methionine metabolism pathway
INOH
INOH website
Glycine Serine metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL D3Z221
UniProt Splice Variant
Entrez Gene 231691
UniGene
RefSeq NM_145565 XM_006530298
OMIM
CCDS CCDS19619
HPRD
IMGT
MGI ID MGI:98270
MGI Symbol Sds
EMBL AC129553
GenPept
RNA Seq Atlas 231691

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca