Homo sapiens Gene: UACA
Summary
InnateDB Gene IDBG-19585.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UACA
Gene Name uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137831
Encoded Proteins
uveal autoantigen with coiled-coil domains and ankyrin repeats
uveal autoantigen with coiled-coil domains and ankyrin repeats
uveal autoantigen with coiled-coil domains and ankyrin repeats
uveal autoantigen with coiled-coil domains and ankyrin repeats
uveal autoantigen with coiled-coil domains and ankyrin repeats
uveal autoantigen with coiled-coil domains and ankyrin repeats
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:70654554-70763593
Strand Reverse strand
Band q23
Transcripts
ENST00000322954 ENSP00000314556
ENST00000379983 ENSP00000369319
ENST00000560441 ENSP00000454018
ENST00000559206
ENST00000560831
ENST00000539319 ENSP00000438667
ENST00000558758 ENSP00000453865
ENST00000559290
ENST00000558308
ENST00000560523
ENST00000559156
ENST00000560951
ENST00000559183
ENST00000560167 ENSP00000453616
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411 response to UV
GO:0042307 positive regulation of protein import into nucleus
GO:0042347 negative regulation of NF-kappaB import into nucleus
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050728 negative regulation of inflammatory response
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0043293 apoptosome
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.108049 Hs.602322 Hs.622978
RefSeq NM_001008224 NM_018003 XM_005254527
HUGO
OMIM
CCDS CCDS10235 CCDS32280
HPRD 11657
IMGT
EMBL
GenPept
RNA Seq Atlas