Mus musculus Gene: Parp3
Summary
InnateDB Gene IDBG-196245.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Parp3
Gene Name poly (ADP-ribose) polymerase family, member 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000023249
Encoded Proteins
poly (ADP-ribose) polymerase family, member 3
poly (ADP-ribose) polymerase family, member 3
poly (ADP-ribose) polymerase family, member 3
poly (ADP-ribose) polymerase family, member 3
poly (ADP-ribose) polymerase family, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000041880:
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:106470322-106476949
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000067218 ENSMUSP00000064513
ENSMUST00000112479 ENSMUSP00000108098
ENSMUST00000123555 ENSMUSP00000123054
ENSMUST00000145396
ENSMUST00000139362
ENSMUST00000156426 ENSMUSP00000117329
ENSMUST00000140029
ENSMUST00000125850 ENSMUSP00000119244
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
Biological Process
GO:0000723 telomere maintenance
GO:0006302 double-strand break repair
GO:0006471 protein ADP-ribosylation
GO:0051106 positive regulation of DNA ligation
GO:0060236 regulation of mitotic spindle organization
GO:1990166 protein localization to site of double-strand break
Cellular Component
GO:0035861 site of double-strand break
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Base excision repair pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Base excision repair pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL E9PX17 Q8BHN6
UniProt Splice Variant
Entrez Gene 235587
UniGene Mm.273659
RefSeq NM_145619 XM_006511717 XM_006511718 XM_006511719 XM_006511720
OMIM
CCDS CCDS23480
HPRD
IMGT
MGI ID MGI:1891258
MGI Symbol Parp3
EMBL AC151729 AY046316 AY046317
GenPept AAL08055 AAL08056
RNA Seq Atlas 235587