InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cox4i1

Summary

InnateDB Gene

IDBG-196484.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cox4i1

Gene Name

cytochrome c oxidase subunit IV isoform 1

Synonyms

AL024441; COX; COX IV-1; Cox4; Cox4a; COXIV; IV-1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031818

Encoded Proteins

IDBP-196486

cytochrome c oxidase subunit IV isoform 1

IDBP-716304

IDBP-717901

IDBP-717082

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131143:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq, Jul 2008]
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3\' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:120668222-120674207

Strand

Forward strand

Band

Transcripts

ENSMUST00000034276	ENSMUSP00000034276
ENSMUST00000181026
ENSMUST00000181795	ENSMUSP00000138063
ENSMUST00000181847	ENSMUSP00000138053
ENSMUST00000180856
ENSMUST00000181586	ENSMUSP00000138019
ENSMUST00000181172

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.