Mus musculus Gene: B3galt2
Summary
InnateDB Gene IDBG-196979.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3galt2
Gene Name UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033849
Encoded Proteins
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162630:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:143640664-143654614
Strand Forward strand
Band F
Transcripts
ENSMUST00000038252 ENSMUSP00000046118
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0009312 oligosaccharide biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt O54905
TrEMBL
UniProt Splice Variant
Entrez Gene 26878
UniGene Mm.285580 Mm.443618 Mm.448703
RefSeq NM_020025
OMIM
CCDS CCDS15342
HPRD
IMGT
MGI ID MGI:1349461
MGI Symbol B3galt2
EMBL AB039144 AB039145 AB039146 AB039147 AB039148 AB039149 AB039150 AB039151 AB039152 AF029791 AK034371 AK036141 AK083168 BC046322
GenPept AAC53524 AAH46322 BAB68668 BAB68669 BAB68670 BAB68671 BAB68672 BAB68673 BAB68674 BAB68675 BAB68676 BAC28688 BAC29317 BAC38793
RNA Seq Atlas 26878