Mus musculus Gene: Meis2
Summary
InnateDB Gene IDBG-197577.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Meis2
Gene Name Meis homeobox 2
Synonyms A430109D20Rik; Mrg1; Stra10;
Species Mus musculus
Ensembl Gene ENSMUSG00000027210
Encoded Proteins
Meis homeobox 2
Meis homeobox 2
Meis homeobox 2
Meis homeobox 2
Meis homeobox 2
Meis homeobox 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134138:
This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a homeobox protein belonging to the TALE (\'three amino acid loop extension\') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:115863064-116065839
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000102538 ENSMUSP00000099597
ENSMUST00000028639 ENSMUSP00000028639
ENSMUST00000074285 ENSMUSP00000073898
ENSMUST00000110908 ENSMUSP00000106533
ENSMUST00000110907 ENSMUSP00000106532
ENSMUST00000110906 ENSMUSP00000106531
ENSMUST00000120995
ENSMUST00000118654
ENSMUST00000151279
ENSMUST00000149217
ENSMUST00000150477
ENSMUST00000154671
ENSMUST00000140461
ENSMUST00000135543
ENSMUST00000134314
ENSMUST00000138526
ENSMUST00000133990
ENSMUST00000177493
ENSMUST00000189640
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 11 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003712 transcription cofactor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001654 eye development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009612 response to mechanical stimulus
GO:0031016 pancreas development
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0070848 response to growth factor
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt P97367
TrEMBL B1AWK4 Q3TYM2 Q3UJ35 Q6GU28
UniProt Splice Variant
Entrez Gene 17536
UniGene Mm.247566
RefSeq NM_001136072 NM_001159567 NM_001159568 NM_001159569 NM_001159570 NM_010825 XM_006498866 XM_006498867
OMIM
CCDS CCDS16568 CCDS50664 CCDS50665 CCDS50666 CCDS50667 CCDS50668
HPRD
IMGT
MGI ID MGI:108564
MGI Symbol Meis2
EMBL AJ000504 AJ000505 AJ000506 AJ000507 AK146633 AK158513 AL772135 AL929037 BC017375 U57343 U68383 U68384
GenPept AAB19193 AAB19194 AAC52948 AAH17375 BAE27320 BAE34540 CAA04138 CAA04139 CAA04140 CAA04141
RNA Seq Atlas 17536