Version 5.4
Mus musculus Gene: Lmo4
Summary
InnateDB Gene IDBG-197587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lmo4
Gene Name LIM domain only 4
Synonyms A730077C12Rik; Crp3; Etohi4
Species Mus musculus
Ensembl Gene ENSMUSG00000028266
Encoded Proteins
IDBP-400363
LIM domain only 4
IDBP-400362
LIM domain only 4
IDBP-400361
LIM domain only 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143013:
This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:144188530-144205220
Strand Reverse strand
Band H2
Transcripts
ENSMUST00000120539 ENSMUSP00000113840
ENSMUST00000121796 ENSMUSP00000113513
ENSMUST00000121112 ENSMUSP00000113865
ENSMUST00000148128
ENSMUST00000134961
ENSMUST00000124891
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001158 enhancer sequence-specific DNA binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
Biological Process
GO:0001843 neural tube closure
GO:0003281 ventricular septum development
GO:0006366 transcription from RNA polymerase II promoter
GO:0021514 ventral spinal cord interneuron differentiation
GO:0021522 spinal cord motor neuron differentiation
GO:0021527 spinal cord association neuron differentiation
GO:0031333 negative regulation of protein complex assembly
GO:0042659 regulation of cell fate specification
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048538 thymus development
GO:0050865 regulation of cell activation
Cellular Component
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143013
View Gene Order
ENSBTAG00000000305
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
shp2_pathway
SHP2 signaling
il6_7pathway
IL6-mediated signaling events
Cross-References
SwissProt P61969
TrEMBL Q542S1
UniProt Splice Variant
Entrez Gene 16911
UniGene Mm.29187 Mm.485977
RefSeq NM_001161769 NM_001161770 NM_010723
OMIM
CCDS CCDS51085
HPRD
IMGT
MGI ID MGI:109360
MGI Symbol Lmo4
EMBL AF074600 AF096996 AF102817 AK080534 AK138278 AK159590 BC003488 BC004661 BC010278 BC100382 CH466532
GenPept AAC62958 AAC83789 AAC98510 AAH03488 AAH10278 AAI00383 BAC37938 BAE23609 BAE35210 EDL12031 EDL12032 EDL12033
RNA Seq Atlas 16911

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca