Version 5.4
Mus musculus Gene: Cdk10
Summary
InnateDB Gene IDBG-198497.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdk10
Gene Name cyclin-dependent kinase 10
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033862
Encoded Proteins
IDBP-198499
cyclin-dependent kinase 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the CDK (cyclin-dependent kinase) subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. The human ortholog has been shown to play a role in cellular proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 1. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:123224841-123232250
Strand Forward strand
Band E1
Transcripts
ENSMUST00000036880 ENSMUSP00000045527
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007049 cell cycle
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185324
View Gene Order
ENSBTAG00000033333
Not yet available
Cross-References
SwissProt Q3UMM4
TrEMBL
UniProt Splice Variant
Entrez Gene 234854
UniGene Mm.190984
RefSeq NM_194444 NM_194446
OMIM
CCDS CCDS22751
HPRD
IMGT
MGI ID MGI:2448549
MGI Symbol Cdk10
EMBL AK133918 AK144801 DQ288857
GenPept ABB96224 BAE21925 BAE26074
RNA Seq Atlas 234854

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca