Version 5.4
| Mus musculus Gene: Dnase2b | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-199181.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Dnase2b | ||||||
| Gene Name | deoxyribonuclease II beta | ||||||
| Synonyms | AI526873; Dlad; DnaseIIb | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000028185 | ||||||
| Encoded Proteins |
deoxyribonuclease II beta
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137976:
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 3:146580985-146596612 | ||||||
| Strand | Reverse strand | ||||||
| Band | H2 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Lysosome pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Lysosome pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q9QY48 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 56629 | ||||||
| UniGene | Mm.25853 | ||||||
| RefSeq | NM_019957 XM_006501763 XM_006501764 | ||||||
| OMIM | |||||||
| CCDS | CCDS17904 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1913283 | ||||||
| MGI Symbol | Dnase2b | ||||||
| EMBL | AF128888 AF334603 AF334604 AF334605 AF334606 AF334607 AF334608 AK079224 BC075661 | ||||||
| GenPept | AAF05082 AAH75661 AAL34450 BAC37579 | ||||||
| RNA Seq Atlas | 56629 | ||||||