Mus musculus Gene: Neu3
Summary
InnateDB Gene IDBG-200895.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neu3
Gene Name neuraminidase 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035239
Encoded Proteins
neuraminidase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162139:
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:99811439-99828417
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000036331 ENSMUSP00000045222
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016997 alpha-sialidase activity
GO:0052794 exo-alpha-(2->3)-sialidase activity
GO:0052795 exo-alpha-(2->6)-sialidase activity
GO:0052796 exo-alpha-(2->8)-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006689 ganglioside catabolic process
GO:0009313 oligosaccharide catabolic process
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Metabolism of lipids and lipoproteins pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
KEGG
Sphingolipid metabolism pathway
Other glycan degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Metabolism pathway
KEGG
Sphingolipid metabolism pathway
Other glycan degradation pathway
INOH
PID NCI
Cross-References
SwissProt Q9JMH7
TrEMBL Q543I9
UniProt Splice Variant
Entrez Gene 50877
UniGene Mm.103703 Mm.444421
RefSeq NM_016720
OMIM
CCDS CCDS21489
HPRD
IMGT
MGI ID MGI:1355305
MGI Symbol Neu3
EMBL AB026842 AK050428 AK134405 BC116892 BC116924 CH466531
GenPept AAI16893 AAI16925 BAA92868 BAC34251 BAE22130 EDL16409
RNA Seq Atlas 50877