Version 5.4
Mus musculus Gene: Pfkfb4
Summary
InnateDB Gene IDBG-200964.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pfkfb4
Gene Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025648
Encoded Proteins
IDBP-200966
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
IDBP-534731
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
IDBP-538964
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
IDBP-535458
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
IDBP-535390
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114268:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:108991902-109032223
Strand Forward strand
Band F2
Transcripts
ENSMUST00000051873 ENSMUSP00000057197
ENSMUST00000147989 ENSMUSP00000117523
ENSMUST00000154190
ENSMUST00000137818 ENSMUSP00000115966
ENSMUST00000136534 ENSMUSP00000116001
ENSMUST00000131344
ENSMUST00000152220
ENSMUST00000125336 ENSMUSP00000116738
ENSMUST00000129526
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 ATP binding
Biological Process
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0016311 dephosphorylation
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000114268
View Gene Order
ENSBTAG00000006752
Not yet available
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_232322
Glycolysis pathway
REACT_261601
Glucose metabolism pathway
REACT_188937
Metabolism pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
mmu00051
Fructose and mannose metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1383
Glycolysis pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_723
Glucose metabolism pathway
REACT_200833
Glycogen storage diseases pathway
KEGG
hsa00051
Fructose and mannose metabolism pathway
INOH
INOH website
Fructose Mannose metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL D3Z465
UniProt Splice Variant
Entrez Gene 270198
UniGene Mm.132391
RefSeq NM_173019 XM_006512138
OMIM
CCDS CCDS23541
HPRD
IMGT
MGI ID MGI:2687284
MGI Symbol Pfkfb4
EMBL AC140383
GenPept
RNA Seq Atlas 270198

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca