Mus musculus Gene: Pigf
Summary
InnateDB Gene IDBG-201296.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigf
Gene Name phosphatidylinositol glycan anchor biosynthesis, class F
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024145
Encoded Proteins
phosphatidylinositol glycan anchor biosynthesis, class F
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151665:
This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:86997256-87025406
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000024957 ENSMUSP00000024957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Metabolism of proteins pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt O09101
TrEMBL
UniProt Splice Variant
Entrez Gene 18701
UniGene Mm.219685
RefSeq NM_008838 XM_006523831
OMIM
CCDS CCDS29011
HPRD
IMGT
MGI ID MGI:99462
MGI Symbol Pigf
EMBL D50264
GenPept BAA08818
RNA Seq Atlas 18701