Version 5.4
Mus musculus Gene: Stx2
Summary
InnateDB Gene IDBG-201716.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx2
Gene Name syntaxin 2
Synonyms AW538950; Epim; G1-536-1; repro34; Syn-2
Species Mus musculus
Ensembl Gene ENSMUSG00000029428
Encoded Proteins
IDBP-201718
syntaxin 2
IDBP-201720
syntaxin 2
IDBP-537287
syntaxin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111450:
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:128984557-129008574
Strand Reverse strand
Band G1.3
Transcripts
ENSMUST00000031378 ENSMUSP00000031378
ENSMUST00000100680 ENSMUSP00000098247
ENSMUST00000128448
ENSMUST00000144846
ENSMUST00000141492
ENSMUST00000151712
ENSMUST00000149877 ENSMUSP00000118220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0007340 acrosome reaction
GO:0007566 embryo implantation
GO:0010468 regulation of gene expression
GO:0016192 vesicle-mediated transport
GO:0030154 cell differentiation
GO:0030193 regulation of blood coagulation
Cellular Component
GO:0005911 cell-cell junction
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111450
View Gene Order
ENSBTAG00000007988
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.260716 Mm.445898
RefSeq NM_001286033 NM_001286034 NM_007941 XM_006504278
OMIM
CCDS CCDS19692 CCDS71672
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca