|Homo sapiens Gene: DSG1|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||desmoglein 1|
|Synonyms||CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1;|
|Useful resources||Stemformatics EHFPI ImmGen|
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 18:31318089-31357029|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Apoptotic execution phase pathway
Apoptotic cleavage of cell adhesion proteins pathway
Apoptotic cleavage of cellular proteins pathway
Staphylococcus aureus infection pathway
|UniProt Splice Variant|
|RNA Seq Atlas|