Version 5.4
Mus musculus Gene: Crcp
Summary
InnateDB Gene IDBG-202209.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crcp
Gene Name calcitonin gene-related peptide-receptor component protein
Synonyms AL022669
Species Mus musculus
Ensembl Gene ENSMUSG00000025532
Encoded Proteins
IDBP-202211
calcitonin gene-related peptide-receptor component protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241258:
This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:130029290-130060789
Strand Forward strand
Band G1.3
Transcripts
ENSMUST00000026608 ENSMUSP00000026608
ENSMUST00000156729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0001635 calcitonin gene-related polypeptide receptor activity
GO:0003824 catalytic activity
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0007218 neuropeptide signaling pathway
GO:0044237 cellular metabolic process
GO:0045087 innate immune response
GO:0051607 defense response to virus
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0009360 DNA polymerase III complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000241258
View Gene Order
ENSBTAG00000037489
Not yet available
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_233104
RNA Polymerase III Transcription Initiation pathway
REACT_250309
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_230745
Immune System pathway
REACT_251592
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_261233
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_218897
Cytosolic sensors of pathogen-associated DNA pathway
REACT_233572
Gene Expression pathway
REACT_221403
RNA Polymerase III Transcription Termination pathway
REACT_237241
RNA Polymerase III Transcription pathway
REACT_240508
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_205207
RNA Polymerase III Chain Elongation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_63
RNA Polymerase III Transcription Termination pathway
REACT_756
RNA Polymerase III Chain Elongation pathway
REACT_571
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_1036
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_347
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_118823
Cytosolic sensors of pathogen-associated DNA pathway
REACT_71
Gene Expression pathway
REACT_216178
RNA Polymerase III Transcription pathway
REACT_206651
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_220514
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_220974
Cytosolic sensors of pathogen-associated DNA pathway
REACT_203707
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_226022
Gene Expression pathway
REACT_213138
Immune System pathway
REACT_212144
RNA Polymerase III Transcription Initiation pathway
REACT_209748
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_216714
Innate Immune System pathway
REACT_203737
RNA Polymerase III Chain Elongation pathway
REACT_221998
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_224876
RNA Polymerase III Transcription Termination pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O35427
TrEMBL
UniProt Splice Variant
Entrez Gene 12909
UniGene Mm.18072
RefSeq NM_007761
OMIM
CCDS CCDS19706
HPRD
IMGT
MGI ID MGI:1100818
MGI Symbol Crcp
EMBL AF028242 AF118271 BC012676
GenPept AAB84046 AAD17244 AAH12676
RNA Seq Atlas 12909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca