Version 5.4
Mus musculus Gene: Sbds
Summary
InnateDB Gene IDBG-202307.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sbds
Gene Name Shwachman-Bodian-Diamond syndrome homolog (human)
Synonyms 4733401P19Rik; AI836084; CGI-97; SDS
Species Mus musculus
Ensembl Gene ENSMUSG00000025337
Encoded Proteins
IDBP-202309
Shwachman-Bodian-Diamond syndrome homolog (human)
IDBP-542974
Shwachman-Bodian-Diamond syndrome homolog (human)
IDBP-542975
Shwachman-Bodian-Diamond syndrome homolog (human)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126524:
This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:130245731-130255530
Strand Reverse strand
Band G1.3
Transcripts
ENSMUST00000026387 ENSMUSP00000026387
ENSMUST00000139211 ENSMUSP00000117348
ENSMUST00000125625 ENSMUSP00000115494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0019843 rRNA binding
GO:0043022 ribosome binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001833 inner cell mass cell proliferation
GO:0006364 rRNA processing
GO:0008283 cell proliferation
GO:0030282 bone mineralization
GO:0030595 leukocyte chemotaxis
GO:0042254 ribosome biogenesis
GO:0042256 mature ribosome assembly
GO:0042273 ribosomal large subunit biogenesis
GO:0043148 mitotic spindle stabilization
GO:0048539 bone marrow development
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000126524
View Gene Order
ENSBTAG00000004051
Not yet available
Cross-References
SwissProt P70122
TrEMBL D6REV5 F6TN03
UniProt Splice Variant
Entrez Gene 66711
UniGene Mm.280484
RefSeq NM_023248 XM_006504490
OMIM
CCDS CCDS19710
HPRD
IMGT
MGI ID MGI:1913961
MGI Symbol Sbds
EMBL AC113029 AK005079 AK014648 AK019228 AK168847 BC003849 X99668
GenPept AAH03849 BAB23803 BAB29487 BAB31612 BAE40670 CAA67982
RNA Seq Atlas 66711

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca