InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Aldh9a1

Summary

InnateDB Gene

IDBG-203236.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aldh9a1

Gene Name

aldehyde dehydrogenase 9, subfamily A1

Synonyms

AA139417; Abaldh; ESTM40; TMABA-DH; Tmabadh

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026687

Encoded Proteins

IDBP-203238

aldehyde dehydrogenase 9, subfamily A1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143149:
This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:167349991-167368530

Strand

Forward strand

Band

H2.3

Transcripts

ENSMUST00000028004

ENSMUSP00000028004

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004029	aldehyde dehydrogenase (NAD) activity
GO:0016491	oxidoreductase activity
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0019145	aminobutyraldehyde dehydrogenase activity
GO:0042803	protein homodimerization activity
GO:0043176	amine binding
GO:0047105	4-trimethylammoniobutyraldehyde dehydrogenase activity
GO:0051287	NAD binding

Biological Process

GO:0001822	kidney development
GO:0001889	liver development
GO:0006081	cellular aldehyde metabolic process
GO:0008152	metabolic process
GO:0009437	carnitine metabolic process
GO:0042136	neurotransmitter biosynthetic process
GO:0045329	carnitine biosynthetic process
GO:0055114	oxidation-reduction process