Version 5.4
Mus musculus Gene: Ksr1
Summary
InnateDB Gene IDBG-203299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ksr1
Gene Name kinase suppressor of ras 1
Synonyms AW492498; B-KSR1; D11Bhm183e; D11Bhm184e; hb; Ksr; RSU2
Species Mus musculus
Ensembl Gene ENSMUSG00000018334
Encoded Proteins
IDBP-203303
kinase suppressor of ras 1
IDBP-264900
kinase suppressor of ras 1
IDBP-539434
kinase suppressor of ras 1
IDBP-542781
kinase suppressor of ras 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141068:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:79013440-79146407
Strand Reverse strand
Band B5
Transcripts
ENSMUST00000018478 ENSMUSP00000018478
ENSMUST00000108264 ENSMUSP00000103899
ENSMUST00000141409 ENSMUSP00000116407
ENSMUST00000129463 ENSMUSP00000114538
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 65 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 65 [view]
Protein-Protein 65 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005078 MAP-kinase scaffold activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0035556 intracellular signal transduction
GO:0043410 positive regulation of MAPK cascade
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141068
View Gene Order
ENSBTAG00000006601
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
ceramide_pathway
Ceramide signaling pathway
erbb1_downstream_pathway
ErbB1 downstream signaling
pdgfrbpathway
PDGFR-beta signaling pathway
Cross-References
SwissProt
TrEMBL Q5SXE4
UniProt Splice Variant
Entrez Gene 16706
UniGene Mm.397247
RefSeq NM_013571
OMIM
CCDS CCDS25117
HPRD
IMGT
MGI ID MGI:105051
MGI Symbol Ksr1
EMBL AL592551
GenPept
RNA Seq Atlas 16706

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca