Version 5.4
Mus musculus Gene: Slamf1
Summary
InnateDB Gene IDBG-204832.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slamf1
Gene Name signaling lymphocytic activation molecule family member 1
Synonyms 4933415F16; AA177906; CD150; CDw150; ESTM51; IPO-3; Slam
Species Mus musculus
Ensembl Gene ENSMUSG00000015316
Encoded Proteins
IDBP-204834
signaling lymphocytic activation molecule family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 18501771
[Homo sapiens] SLAMF1 is one of nine SLAM-family genes, a subfamily of the immunoglobulin superfamily, that encode differentially expressed cell-surface receptors of hematopoietic cells. SLAM and SLAM-associated protein (SAP) gene families control innate and adaptive immune responses
PMID 19079134
[Homo sapiens] SLAMF1 is one of nine SLAM-family genes and SLAM receptors and SLAM-associated proteins (SAPs) influence lymphocyte interactions, development and function.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117090:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:171767127-171801184
Strand Forward strand
Band H3
Transcripts
ENSMUST00000015460 ENSMUSP00000015460
ENSMUST00000163992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0031338 regulation of vesicle fusion
GO:0046649 lymphocyte activation
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0045335 phagocytic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117090
View Gene Order
ENSBTAG00000007927
Not yet available
Cross-References
SwissProt Q9QUM4
TrEMBL Q3TEM6 Q544K1
UniProt Splice Variant
Entrez Gene 27218
UniGene Mm.103648 Mm.413296
RefSeq NM_013730 XM_006496872 XM_006496873
OMIM
CCDS CCDS15502
HPRD
IMGT
MGI ID MGI:1351314
MGI Symbol Slamf1
EMBL AB196796 AB196798 AB196799 AF149791 AF149792 AF160990 AF164519 AF164520 AF164521 AF164522 AF164523 AK036429 AK156445 AK169547 BC117095 BC117099 CH466520
GenPept AAF13818 AAF14535 AAF22231 AAF22232 AAI17096 AAI17100 BAC29424 BAE33713 BAE41222 BAE96299 BAE96301 BAE96302 EDL39053
RNA Seq Atlas 27218

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca