Version 5.4
Homo sapiens Gene: SLAMF1
Summary
InnateDB Gene IDBG-104073.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLAMF1
Gene Name signaling lymphocytic activation molecule family member 1
Synonyms CD150; CDw150; SLAM
Species Homo sapiens
Ensembl Gene ENSG00000117090
Encoded Proteins
IDBP-104075
signaling lymphocytic activation molecule family member 1
IDBP-104077
signaling lymphocytic activation molecule family member 1
IDBP-589629
signaling lymphocytic activation molecule family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 18501771
SLAMF1 is one of nine SLAM-family genes, a subfamily of the immunoglobulin superfamily, that encode differentially expressed cell-surface receptors of hematopoietic cells. SLAM and SLAM-associated protein (SAP) gene families control innate and adaptive immune responses
PMID 19079134
SLAMF1 is one of nine SLAM-family genes and SLAM receptors and SLAM-associated proteins (SAPs) influence lymphocyte interactions, development and function.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:160608100-160647295
Strand Reverse strand
Band q23.3
Transcripts
ENST00000302035 ENSP00000306190
ENST00000235739 ENSP00000235739
ENST00000494463
ENST00000538290 ENSP00000438406
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
GO:0004872 receptor activity
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0008284 positive regulation of cell proliferation
GO:0016032 viral process
GO:0031338 regulation of vesicle fusion
GO:0045087 innate immune response (InnateDB)
GO:0046649 lymphocyte activation
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0045335 phagocytic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015316
View Gene Order
ENSBTAG00000007927
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.523660
RefSeq NM_003037 XM_005245457
HUGO
OMIM
CCDS CCDS1207
HPRD 04603
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca