Version 5.4
Homo sapiens Gene: SLC7A1
Summary
InnateDB Gene IDBG-20593.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC7A1
Gene Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Synonyms ATRC1; CAT-1; ERR; HCAT1; REC1L
Species Homo sapiens
Ensembl Gene ENSG00000139514
Encoded Proteins
IDBP-20595
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
IDBP-363217
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:29509410-29595688
Strand Reverse strand
Band q12.3
Transcripts
ENST00000380752 ENSP00000370128
ENST00000450494 ENSP00000390092
ENST00000473577
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015171 amino acid transmembrane transporter activity
GO:0015181 arginine transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0006811 ion transport
GO:0006865 amino acid transport
GO:0015809 arginine transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041313
View Gene Order
ENSBTAG00000018577
Not yet available
Pathways
NETPATH
REACTOME
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P30825
TrEMBL A0A024RDQ9 Q5JR49
UniProt Splice Variant
Entrez Gene 6541
UniGene Hs.14846 Hs.596743 Hs.604662
RefSeq NM_003045 XM_005266507
HUGO HGNC:11057
OMIM 104615
CCDS CCDS9333
HPRD
IMGT
EMBL AF078107 AL596114 BC063303 BC069358 BC115407 CH471075 X57303 X59155
GenPept AAC27721 AAH63303 AAH69358 AAI15408 CAA40560 CAA41869 CAI39913 EAX08443 EAX08444
RNA Seq Atlas 6541

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca