Homo sapiens Gene: HEBP1
Summary
InnateDB Gene IDBG-20636.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HEBP1
Gene Name heme binding protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000013583
Encoded Proteins
heme binding protein 1
heme binding protein 1
heme binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:12974864-13000273
Strand Reverse strand
Band p13.1
Transcripts
ENST00000014930 ENSP00000014930
ENST00000540916
ENST00000535636 ENSP00000442020
ENST00000536942 ENSP00000441678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0020037 heme binding
Biological Process
GO:0007623 circadian rhythm
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Class A/1 (Rhodopsin-like receptors) pathway
Formyl peptide receptors bind formyl peptides and many other ligands pathway
Signaling by GPCR pathway
Peptide ligand-binding receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
GPCR ligand binding pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.737726
RefSeq NM_015987
HUGO
OMIM
CCDS CCDS31749
HPRD 16162
IMGT
EMBL
GenPept
RNA Seq Atlas