Homo sapiens Protein: HEBP1
Summary
InnateDB Protein IDBP-20638.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HEBP1
Protein Name heme binding protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000014930
InnateDB Gene IDBG-20636 (HEBP1)
Protein Structure
UniProt Annotation
Function May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N- methylprotoporphyrin with similar affinities. {ECO:0000269PubMed:12413491}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:12413491}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0020037 heme binding
Biological Process
GO:0007623 circadian rhythm
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR006917 SOUL haem-binding protein
IPR011256 Regulatory factor, effector binding domain
PFAM PF04832
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NRV9
PhosphoSite PhosphoSite-Q9NRV9
TrEMBL F5GWX2
UniProt Splice Variant
Entrez Gene 50865
UniGene Hs.737726
RefSeq NP_057071
HUGO HGNC:17176
OMIM 605826
CCDS CCDS31749
HPRD 16162
IMGT
EMBL AC007688 AF117615 AF167473 AK289877 BC016277 BT007294 CH471094
GenPept AAD32098 AAF89618 AAH16277 AAP35958 BAF82566 EAW96295 EAW96296