Version 5.4
Mus musculus Gene: Rras2
Summary
InnateDB Gene IDBG-207188.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rras2
Gene Name related RAS viral (r-ras) oncogene homolog 2
Synonyms 2610016H24Rik; C86394; TC21
Species Mus musculus
Ensembl Gene ENSMUSG00000055723
Encoded Proteins
IDBP-207190
related RAS viral (r-ras) oncogene homolog 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133818:
This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:114046785-114117781
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000069449 ENSMUSP00000069752
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0009987 cellular process
GO:0015031 protein transport
GO:0030335 positive regulation of cell migration
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000133818
View Gene Order
ENSBTAG00000011905
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04530
Tight junction pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04010
MAPK signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_12
BCR pathway
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04010
MAPK signaling pathway pathway
hsa04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt P62071
TrEMBL Q9CTF6
UniProt Splice Variant
Entrez Gene 66922
UniGene Mm.401109
RefSeq NM_025846
OMIM
CCDS CCDS21758
HPRD
IMGT
MGI ID MGI:1914172
MGI Symbol Rras2
EMBL AK003733 AK011419 AK078870 AK172037 BC003871
GenPept AAH03871 BAB22967 BAB27607 BAC37432 BAE42790
RNA Seq Atlas 66922

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca