InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Pde3b

Summary

InnateDB Gene

IDBG-207234.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pde3b

Gene Name

phosphodiesterase 3B, cGMP-inhibited

Synonyms

9830102A01Rik; AI847709

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030671

Encoded Proteins

IDBP-207236

phosphodiesterase 3B, cGMP-inhibited

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152270:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:114415281-114539251

Strand

Forward strand

Band

Transcripts

ENSMUST00000032909	ENSMUSP00000032909
ENSMUST00000140007
ENSMUST00000149455

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006198	cAMP catabolic process
GO:0007162	negative regulation of cell adhesion
GO:0007165	signal transduction
GO:0016525	negative regulation of angiogenesis
GO:0031018	endocrine pancreas development
GO:0042593	glucose homeostasis
GO:0050796	regulation of insulin secretion
GO:0050995	negative regulation of lipid catabolic process