Version 5.4
Mus musculus Gene: Coq7
Summary
InnateDB Gene IDBG-207625.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Coq7
Gene Name demethyl-Q 7
Synonyms clk-1
Species Mus musculus
Ensembl Gene ENSMUSG00000030652
Encoded Proteins
IDBP-207627
demethyl-Q 7
IDBP-207629
demethyl-Q 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167186:
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:118509659-118533356
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000098090 ENSMUSP00000095695
ENSMUST00000032887 ENSMUSP00000032887
ENSMUST00000127700
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0001306 age-dependent response to oxidative stress
GO:0001701 in utero embryonic development
GO:0001841 neural tube formation
GO:0006744 ubiquinone biosynthetic process
GO:0006979 response to oxidative stress
GO:0008340 determination of adult lifespan
GO:0022008 neurogenesis
GO:0022904 respiratory electron transport chain
GO:0034599 cellular response to oxidative stress
GO:0042775 mitochondrial ATP synthesis coupled electron transport
GO:0055114 oxidation-reduction process
GO:0070584 mitochondrion morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167186
View Gene Order
ENSBTAG00000021242
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_196568
Ubiquinol biosynthesis pathway
KEGG
mmu00130
Ubiquinone and other terpenoid-quinone biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160111
Ubiquinol biosynthesis pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_219139
Metabolism pathway
REACT_227457
Ubiquinol biosynthesis pathway
KEGG
hsa00130
Ubiquinone and other terpenoid-quinone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3TYT1
UniProt Splice Variant
Entrez Gene 12850
UniGene Mm.20634 Mm.470801
RefSeq XM_006507296 NM_009940
OMIM
CCDS CCDS21771
HPRD
IMGT
MGI ID MGI:107207
MGI Symbol Coq7
EMBL AC122912 AK158380
GenPept BAE34481
RNA Seq Atlas 12850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca