Mus musculus Gene: Nptx2
InnateDB Gene IDBG-208143.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nptx2
Gene Name neuronal pentraxin 2
Synonyms Narp; np2
Species Mus musculus
Ensembl Gene ENSMUSG00000059991
Encoded Proteins
neuronal pentraxin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106236:
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:144545887-144557478
Strand Forward strand
Band G2
ENSMUST00000071782 ENSMUSP00000071687
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0005576 extracellular region
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt O70340
UniProt Splice Variant
Entrez Gene 53324
UniGene Mm.396959
RefSeq NM_016789
MGI ID MGI:1858209
MGI Symbol Nptx2
EMBL AF049124 AF318618 BC026054
GenPept AAC05131 AAH26054 AAK06745
RNA Seq Atlas 53324