Version 5.4
| Homo sapiens Gene: NPTX2 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-28612.5 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | NPTX2 | ||||||
| Gene Name | neuronal pentraxin II | ||||||
| Synonyms | NARP; NP-II; NP2 | ||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000106236 | ||||||
| Encoded Proteins |
neuronal pentraxin II
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 7:98617297-98629868 | ||||||
| Strand | Forward strand | ||||||
| Band | q22.1 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||
| SwissProt | P47972 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 4885 | ||||||
| UniGene | Hs.3281 Hs.603562 | ||||||
| RefSeq | NM_002523 | ||||||
| HUGO | HGNC:7953 | ||||||
| OMIM | 600750 | ||||||
| CCDS | CCDS5657 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AC074121 BC009924 BC034781 BC035339 BC048275 CH236956 CH471091 U26662 U29191 U29192 U29193 U29194 U29195 | ||||||
| GenPept | AAA68980 AAA92296 AAH09924 AAH34781 AAH35339 AAH48275 AAQ93363 EAL23889 EAW76705 | ||||||
| RNA Seq Atlas | 4885 | ||||||