Version 5.4
Mus musculus Gene: Sec23b
Summary
InnateDB Gene IDBG-208573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sec23b
Gene Name SEC23B (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027429
Encoded Proteins
IDBP-208577
SEC23B (S. cerevisiae)
IDBP-532235
SEC23B (S. cerevisiae)
IDBP-539378
SEC23B (S. cerevisiae)
IDBP-539078
SEC23B (S. cerevisiae)
IDBP-534014
SEC23B (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101310:
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:144556229-144590749
Strand Forward strand
Band G1
Transcripts
ENSMUST00000028916 ENSMUSP00000028916
ENSMUST00000143573 ENSMUSP00000120972
ENSMUST00000155258 ENSMUSP00000123690
ENSMUST00000143921
ENSMUST00000155876 ENSMUSP00000122884
ENSMUST00000149697 ENSMUSP00000122819
ENSMUST00000128210
ENSMUST00000146487
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0012505 endomembrane system
GO:0030127 COPII vesicle coat
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101310
View Gene Order
ENSBTAG00000018295
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q9D662
TrEMBL A2AN97 A2AN98 A2AN99 A2ANA0
UniProt Splice Variant
Entrez Gene 27054
UniGene Mm.248492 Mm.474057 Mm.487953
RefSeq NM_001252543 NM_001252544 NM_001252545 NM_001281816 NM_019787
OMIM
CCDS CCDS16822
HPRD
IMGT
MGI ID MGI:1350925
MGI Symbol Sec23b
EMBL AF200326 AK014597 AK149693 AK153214 AK166330 AL808119 BC005464 BC011160
GenPept AAF08301 AAH05464 AAH11160 BAB29452 BAE29030 BAE31812 BAE38710 CAM26712
RNA Seq Atlas 27054

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca