Version 5.4
Mus musculus Protein: Sec23b
Summary
InnateDB Protein IDBP-208577.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sec23b
Protein Name SEC23B (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000028916
InnateDB Gene IDBG-208573 (Sec23b)
Protein Structure
UniProt Annotation
Function Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0012505 endomembrane system
GO:0030127 COPII vesicle coat
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1350925
InterPro IPR002035 von Willebrand factor, type A
IPR006895 Zinc finger, Sec23/Sec24-type
IPR006896 Sec23/Sec24, trunk domain
IPR006900 Sec23/Sec24, helical domain
IPR007123 Gelsolin-like domain
IPR012990 Sec23/Sec24 beta-sandwich
PFAM PF00092
PF04810
PF04811
PF04815
PF00626
PF08033
PRINTS
PIRSF
SMART SM00327
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D662
PhosphoSite PhosphoSite-Q9D662
TrEMBL A2ANA0
UniProt Splice Variant
Entrez Gene 27054
UniGene Mm.487953
RefSeq NP_062761
MGI ID
MGI Symbol Sec23b
OMIM
CCDS CCDS16822
HPRD
IMGT
EMBL AF200326 AK014597 AK149693 AK153214 AK166330 AL808119 BC005464 BC011160
GenPept AAF08301 AAH05464 AAH11160 BAB29452 BAE29030 BAE31812 BAE38710 CAM26712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca