Version 5.4
Homo sapiens Gene: GPX8
Summary
InnateDB Gene IDBG-20980.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPX8
Gene Name glutathione peroxidase 8 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164294
Encoded Proteins
IDBP-20982
glutathione peroxidase 8 (putative)
IDBP-474129
glutathione peroxidase 8 (putative)
IDBP-477136
glutathione peroxidase 8 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:55160118-55167071
Strand Forward strand
Band q11.2
Transcripts
ENST00000296734 ENSP00000296734
ENST00000503787 ENSP00000423822
ENST00000511617
ENST00000506123
ENST00000515370 ENSP00000427466
ENST00000502733
ENST00000514317
ENST00000505096
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021760
View Gene Order
ENSBTAG00000021960
Not yet available
Pathways
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_172715
Detoxification of Reactive Oxygen Species pathway
KEGG
hsa00590
Arachidonic acid metabolism pathway
hsa00480
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.289044 Hs.718761 Hs.732562
RefSeq NM_001008397 XM_006714631
HUGO
OMIM
CCDS CCDS34156
HPRD 17416
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca