Mus musculus Gene: Tpx2
Summary
InnateDB Gene IDBG-209892.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tpx2
Gene Name TPX2, microtubule-associated protein homolog (Xenopus laevis)
Synonyms 2610005B21Rik; DIL2; p100; REPP86;
Species Mus musculus
Ensembl Gene ENSMUSG00000027469
Encoded Proteins
TPX2, microtubule-associated protein homolog (Xenopus laevis)
TPX2, microtubule-associated protein homolog (Xenopus laevis)
TPX2, microtubule-associated protein homolog (Xenopus laevis)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088325:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152847964-152895321
Strand Forward strand
Band H1
Transcripts
ENSMUST00000028969 ENSMUSP00000028969
ENSMUST00000109816 ENSMUSP00000105441
ENSMUST00000136407
ENSMUST00000144848
ENSMUST00000143740
ENSMUST00000164120 ENSMUSP00000128888
ENSMUST00000178997 ENSMUSP00000136457
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0006915 apoptotic process
GO:0007067 mitotic nuclear division
GO:0032147 activation of protein kinase activity
GO:0060236 regulation of mitotic spindle organization
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0043203 axon hillock
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
Role of ran in mitotic spindle regulation [Biocarta view]
PID NCI
Aurora A signaling
PLK1 signaling events
Cross-References
SwissProt A2APB8
TrEMBL Q9CT36
UniProt Splice Variant
Entrez Gene 72119
UniGene Mm.407737
RefSeq XM_006500213 NM_001141975 NM_001141976 NM_001141977 NM_001141978 NM_028109 XM_006500214 XM_006500215
OMIM
CCDS CCDS16900
HPRD
IMGT
MGI ID MGI:1919369
MGI Symbol Tpx2
EMBL AK011311 AK153957 AL833801 BC060619 CH466551
GenPept AAH60619 BAB27537 BAE32280 CAM23677 EDL05994
RNA Seq Atlas 72119